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Noninfectious Complications of Peritoneal Dialysis: Implications for Patient and Technique Survival

Brendan B. McCormick^* and Joanne M. Bargman

^* Division of Nephrology, Kidney Research Center, and Department of Medicine, University of Ottawa, Ottawa, and Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Correspondence: Dr. Brendan B. McCormick, 1967 Riverside Drive, Room 527, Ottawa, ON, Canada K1H 7W9. Phone: 613-738-8400, ext. 82893; Fax: 613-738-8337; E-mail: bmccormick{at}ottawahospital.on.ca

Noninfectious complications of peritoneal dialysis (PD) are increasing in relative importance due to success in decreasing the rate of PD peritonitis. Mechanical catheter complications are emerging as an important cause of technique failure at the same time as experience with PD is declining in North America. There is also increasing interest in metabolic complications of PD and in glucose-sparing strategies to reduce the risk for hyperglycemia, hyperinsulinemia, and hyperleptinemia. This clinical commentary focuses on these noninfectious complications of PD.

Copyright © 2008 by the American Society of Nephrology. Online ISSN: 1533-3450 Print ISSN: 1046-6673