2007 JASN IMPACT FACTOR 7.111	HOME   AUTHOR INFO   EDITORIAL BOARD   SUBSCRIBE   FEEDBACK   ALERTS   HELP
advanced	CURRENT ISSUE	ARCHIVES	JASN Express	ONLINE SUBMISSION

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Whittier, W. L. Articles by Korbet, S. M. Search for Related Content PubMed PubMed Citation Articles by Whittier, W. L. Articles by Korbet, S. M. Related Collections Related Article

Timing of Complications in Percutaneous Renal Biopsy

Section of Nephrology, Department of Medicine, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois

Correspondence to Dr. William L. Whittier, 1426 W. Washington Boulevard, Chicago, IL 60607. Phone: 312-850-8434; Fax: 312-850-8431;

ABSTRACT. Percutaneous renal biopsy (PRB) is a safe and effective tool in the diagnosis and management of renal disease; however, the optimal timing of observation after biopsy is not clearly established. With the use of real-time ultrasound guidance, PRB of native kidneys was performed in 750 adult patients at an academic institution by an attending nephrologist or fellow between June 1983 and June 2002. All patients were observed for 23 to 24 h after biopsy for the presence, severity, and timing of complications. Biopsy-related complications occurred in 98 (13%) patients; minor complications occurred in 50 (6.6%) patients, and major complications occurred in 48 (6.4%) patients. One (0.1%) patient died as a result of the biopsy. Multivariate analysis using logistic regression found only serum creatinine at baseline predictive of a complication. Patients with a serum creatinine 5.0 mg/dl were 2.3 times as likely to have a complication (odds ratio, 2.3; 95% confidence interval, 1.3 to 4.1; P < 0.005). Complications were identified in 38 (42%) patients by 4 h, in 61 (67%) patients by 8 h, in 77 (85%) patients by 12 h, and in 81 (89%) patients at 24 h. The PRB remains a safe procedure, but the risk of complication is higher in patients with advanced renal insufficiency. After biopsy, an observation time of up to 24 h remains optimal as an observation period of 8 h risks missing 33% of complications. E-mail: william_whittier@rush.edu

Related Article

This Month’s Highlights
J. Am. Soc. Nephrol. 2004 15: A14-A16. [Full Text] [PDF]

This article has been cited by other articles:

				B. Mackinnon, E. Fraser, K. Simpson, J. G. Fox, and C. Geddes Is it necessary to stop antiplatelet agents before a native renal biopsy? Nephrol. Dial. Transplant., November 1, 2008; 23(11): 3566 - 3570. [Abstract] [Full Text] [PDF]

				M. K. Hatfield, R. A. Beres, S. S. Sane, and G. X. Zaleski Percutaneous Imaging-Guided Solid Organ Core Needle Biopsy: Coaxial Versus Noncoaxial Method Am. J. Roentgenol., February 1, 2008; 190(2): 413 - 417. [Abstract] [Full Text] [PDF]

				A. Pasquariello, M. Innocenti, V. Batini, G. Pasquariello, S. Beati, S. Rindi, S. Paoletti, and V. Panichi Theoretical calculation of optimal depth in the percutaneous native kidney biopsy to drastically reduce bleeding complications and sample inadequacy for histopathological diagnosis Nephrol. Dial. Transplant., December 1, 2007; 22(12): 3516 - 3520. [Abstract] [Full Text] [PDF]

				M. Werner, A. Osadchy, E. Plotkin, J. Berheim, and V. Rathaus Increased Detection of Early Vascular Abnormalities After Renal Biopsies by Color Doppler Sonography J. Ultrasound Med., September 1, 2007; 26(9): 1221 - 1226. [Abstract] [Full Text] [PDF]

				S. D. Weisbord, M. Ramkumar, S. A. LaPidus, D. J. McBride, and P. M. Palevsky Functional renal artery obstruction following percutaneous kidney biopsy Nephrol. Dial. Transplant., June 1, 2005; 20(6): 1274 - 1275. [Full Text] [PDF]

Copyright © 2008 by the American Society of Nephrology. Online ISSN: 1533-3450 Print ISSN: 1046-6673